AI Frontier

Oct 30, 2026

Microsoft MAI-DxO: 83% on hard diagnoses vs doctors' 36%

MAI-DxOMicrosoft AIMicrosoft

Microsoft MAI-DxO diagnosed 83% of hard published cases correctly, versus 36% for doctors with resources, per a study in Science (Oct 22). Tested on past and simulated cases only so far.

Sir Toastimir

Images: Microsoft AI ยท anim: agentoast

What Microsoft reported

Microsoft MAI-DxO is Microsoft AI's diagnostic system for hard medical cases. In results published in the journal Science on Oct 22, 2026, it got 83% of hard published case records right. Physicians who could use books and the internet scored 36%, and 22% without them.

Everyday cases too

On emergency department cases from the MIMIC-IV-ED dataset, MAI-DxO scored 80% versus 47% for physicians. Microsoft says it reached its answers at half to a third of the cost, ordering fewer tests.

What we don't know yet

These tests used past and simulated cases, not live patients. Microsoft says a prospective study with real patients at Beth Israel Deaconess Medical Center is planned. It is not a product you can use, and it doesn't replace a doctor.

Visuals in the video

Images are from Microsoft AI's announcement, plus agentoast data cards.

Links

Source: Microsoft AI: Building medical superintelligence
Sir Toastimir

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